Phase 3 Clinical Trials With Primary Completion Dates in June 2025

This is a list of Phase 3 trials with primary completion dates in June 2025 for companies with a market cap less than $1B. For complete clinical trial coverage, please see our Trial Tracker tool. It includes information on all clinical trials for publicly traded companies, screenable by stock symbol, market cap, disease, completion date, and phase.

The primary completion date is the date that the final subject was examined or received an intervention for the purposes of final collection of data for the primary outcome. It provides advance notice that a company will be announcing trial results in the near future.

SymbolCompanyPrimary Completion DatePhaseNCT IDTitle
APLSApellis Pharmaceuticals, Inc.2025-06-01Phase 3NCT03531255Pegcetacoplan Long Term Safety and Efficacy Extension Study
ASCLFAscletis Pharma Inc.2025-06-01Phase 3NCT05118776Study to Evaluate the Safety and Efficacy of ASC40 Tablets in Combination With Bevacizumab in Subjects With rGBM
AYTUAytu BioPharma, Inc.2025-06-01Phase 3NCT05463679Investigate Efficacy, Safety, and Pharmacokinetics of Enzastaurin for the Prevention of Arterial Events in Patients With Vascular Ehlers-Danlos Syndrome.
BHVNBiohaven Ltd.2025-06-01Phase 3NCT04641143Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder
BSPMBiostar Pharmaceuticals, Inc.2025-06-01Phase 3NCT05430399Utidelone Versus Docetaxel in HER2-negative Locally Advanced or Metastatic Breast Cancer
IONSIonis Pharmaceuticals, Inc.2025-06-01Phase 3NCT05552326A Study of Olezarsen Administered Subcutaneously to Participants With Severe Hypertriglyceridemia
MISTMilestone Pharmaceuticals Inc.2025-06-01Phase 3NCT04952610Etripamil Nasal Spray in Patients With Paroxysmal Supraventricular Tachycardia
NPCENeuroPace, Inc.2025-06-01Phase 3NCT05147571RNS System NAUTILUS Study
PRTAProthena Corporation plc2025-06-01Phase 3NCT04973137A Study to Evaluate the Efficacy and Safety of Birtamimab in Mayo Stage IV Patients with AL Amyloidosis
VTGNVistagen Therapeutics, Inc.2025-06-01Phase 3NCT06358651Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults with Social Anxiety Disorder (PALISADE-3)
XENEXenon Pharmaceuticals Inc.2025-06-01Phase 3NCT05667142A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures