Phase 3 Clinical Trials With Primary Completion Dates in June 2025

This is a list of Phase 3 trials with primary completion dates in June 2025 for companies with a market cap less than $1B. For complete clinical trial coverage, please see our Trial Tracker tool. It includes information on all clinical trials for publicly traded companies, screenable by stock symbol, market cap, disease, completion date, and phase.

The primary completion date is the date that the final subject was examined or received an intervention for the purposes of final collection of data for the primary outcome. It provides advance notice that a company will be announcing trial results in the near future.

Symbol Company Primary Completion Date Phase NCT ID Title
APLS Apellis Pharmaceuticals, Inc. 2025-06-01 Phase 3 NCT03531255 Pegcetacoplan Long Term Safety and Efficacy Extension Study
ASCLF Ascletis Pharma Inc. 2025-06-01 Phase 3 NCT05118776 Study to Evaluate the Safety and Efficacy of ASC40 Tablets in Combination With Bevacizumab in Subjects With rGBM
AYTU Aytu BioPharma, Inc. 2025-06-01 Phase 3 NCT05463679 Investigate Efficacy, Safety, and Pharmacokinetics of Enzastaurin for the Prevention of Arterial Events in Patients With Vascular Ehlers-Danlos Syndrome.
BHVN Biohaven Ltd. 2025-06-01 Phase 3 NCT04641143 Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder
BSPM Biostar Pharmaceuticals, Inc. 2025-06-01 Phase 3 NCT05430399 Utidelone Versus Docetaxel in HER2-negative Locally Advanced or Metastatic Breast Cancer
IONS Ionis Pharmaceuticals, Inc. 2025-06-01 Phase 3 NCT05552326 A Study of Olezarsen Administered Subcutaneously to Participants With Severe Hypertriglyceridemia
MIST Milestone Pharmaceuticals Inc. 2025-06-01 Phase 3 NCT04952610 Etripamil Nasal Spray in Patients With Paroxysmal Supraventricular Tachycardia
NPCE NeuroPace, Inc. 2025-06-01 Phase 3 NCT05147571 RNS System NAUTILUS Study
PRTA Prothena Corporation plc 2025-06-01 Phase 3 NCT04973137 A Study to Evaluate the Efficacy and Safety of Birtamimab in Mayo Stage IV Patients with AL Amyloidosis
VTGN Vistagen Therapeutics, Inc. 2025-06-01 Phase 3 NCT06358651 Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults with Social Anxiety Disorder (PALISADE-3)
XENE Xenon Pharmaceuticals Inc. 2025-06-01 Phase 3 NCT05667142 A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures