Phase 3 Clinical Trials With Primary Completion Dates in August 2026

This is a list of Phase 3 trials with primary completion dates in August 2026 for companies with a market cap less than $1B. For complete clinical trial coverage, please see our Trial Tracker tool. It includes information on all clinical trials for publicly traded companies, screenable by stock symbol, market cap, disease, completion date, and phase.

The primary completion date is the date that the final subject was examined or received an intervention for the purposes of final collection of data for the primary outcome. It provides advance notice that a company will be announcing trial results in the near future.

SymbolCompanyPrimary Completion DatePhaseNCT IDTitle
AKBAAkebia Therapeutics, Inc.2026-08-01Phase 3NCT06901505To Evaluate the Efficacy of Three Times Weekly (TIW) Vadadustat Compared to Standard of Care ESA in Patients With Anemia of CKD Receiving In-Center Hemodialysis
DFTXDefinium Therapeutics, Inc.2026-08-01Phase 3NCT06809595A Phase 3 Trial of MM120 for Generalized Anxiety Disorder (Panorama)
ENSCEnsysce Biosciences, Inc.2026-08-01Phase 3NCT06602271PF614 Analgesic Activity in Acute Postoperative Pain (PF614-301)
EYPTEyePoint, Inc.2026-08-01Phase 3NCT06668064A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUGANO) Primary Efficacy Will be Determined at Week 56
GRFSGrifols, S.A.2026-08-01Phase 3NCT01983241Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin Deficiency (AATD)
IVVDInvivyd, Inc.2026-08-01Phase 3NCT07298434Study of VYD2311 for the Prevention of COVID-19
IVVDInvivyd, Inc.2026-08-01Phase 3NCT07655180Safety and Serum Virus Neutralizing Antibody Responses of VYD2311, a COVID-19 Vaccine, and Coadministered VYD2311 With a COVID-19 Vaccine
KODKodiak Sciences Inc.2026-08-01Phase 3NCT06556368A Study to Evaluate the Efficacy and Safety of Tarcocimab Tedromer and Tabirafusp Tedromer Compared to Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) - DAYBREAK
KPTIKaryopharm Therapeutics Inc.2026-08-01Phase 3NCT05611931Selinexor in Maintenance Therapy After Systemic Therapy for Participants With p53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma
LLYEli Lilly and Company2026-08-01Phase 3NCT06260722Effect of Retatrutide Compared With Semaglutide in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin With or Without SGLT2 Inhibitor (TRANSCEND-T2D-2)
MIRMMirum Pharmaceuticals, Inc.2026-08-01Phase 3NCT07298330A Trial Evaluating Brelovitug vs Delayed Treatment for the Treatment of Chronic Hepatitis Delta Infection (AZURE-4)
MRCHFH.U. Group Holdings, Inc.2026-08-01Phase 3NCT05040464Comparison of Azathioprine to Methotrexate in Combination Therapy With Adalimumab in Crohn's Disease: an Open-label Randomized Controlled Trial
PHVSPharvaris N.V.2026-08-01Phase 3NCT06669754Study of Oral Deucrictibant Extended-Release Tablet for Prophylaxis Against Angioedema Attacks in Adolescents and Adults With HAE
RCUSArcus Biosciences, Inc.2026-08-01Phase 3NCT05568095A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body
SLGLSol-Gel Technologies Ltd.2026-08-01Phase 3NCT06050122Efficacy and Safety of Patidegib Gel 2% for Preventing Basal Cell Carcinomas on the Face of Adults With Gorlin Syndrome
XENEXenon Pharmaceuticals Inc.2026-08-01Phase 3NCT06775379A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder